*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AJ1925000
CHEMICAL NAME           : Acetic acid, pentyl ester
CAS REGISTRY NUMBER     : 628-63-7
BEILSTEIN REFERENCE NO. : 1744753
REFERENCE               : 4-02-00-00152 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 20
MOLECULAR FORMULA       : C7-H14-O2
MOLECULAR WEIGHT        : 130.21
WISWESSER LINE NOTATION : 5OV1
COMPOUND DESCRIPTOR     : Human
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Acetate d'amyle
   * Acetic acid, amyl ester
   * Amyl acetate
   * n-Amyl acetate
   * Amyl acetic ester
   * Amylazetat
   * Amylester kyseliny octove
   * Birnenoel
   * Octan amylu
   * Pear oil
   * Pent-acetate
   * Pent-acetate 28
   * 1-Pentanol acetate
   * Pentyl acetate
   * n-Pentyl acetate
   * 1-Pentyl acetate
   * Primary amyl acetate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Human
DOSE/DURATION           : 300 ppm
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 25,282,1943
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 5000 mg/m3/30M
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AHYGAJ Archiv fuer Hygiene.  (Munich, Fed. Rep. Ger.)  V.1-100, 1883-1928.
   For publisher information, see ZHPMAT.  Volume(issue)/page/year: 78,260,1913
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 7400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,357,1986
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other transferases
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   35,21,1974

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 532 mg/m3 (100 ppm)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   TOXICOLOGY REVIEW
   AMIHAB AMA Archives of Industrial Health.  (Chicago, IL)  V.11-21, 1955-60.
   For publisher information, see AEHLAU.  Volume(issue)/page/year: 21,28,1960

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

   MSHA STANDARD-air:TWA 100 ppm (525 mg/m3)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,12,1971

   OSHA PEL (Gen Indu):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO n-AMYL ACETATE-air:10H TWA 100 ppm
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1226
       No. of Facilities: 4502 (estimated)
       No. of Industries: 48
       No. of Occupations: 56
       No. of Employees: 37718 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M1226
       No. of Facilities: 21065 (estimated)
       No. of Industries: 142
       No. of Occupations: 108
       No. of Employees: 265437 (estimated)
       No. of Female Employees: 91128 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Esters I, 1450
   
   NIOSH Analytical Method, 1996: Volatile organic compound, 2549

 
                            *** END OF RECORD ***