*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : FH5391000
CHEMICAL NAME : 5-beta-Card-20(22)-enolide,
3-beta,14,16-beta-trihydroxy-
CAS REGISTRY NUMBER : 545-26-6
BEILSTEIN REFERENCE NO. : 0096483
REFERENCE : 5-18-04-00385 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C23-H34-O5
MOLECULAR WEIGHT : 390.57
SYNONYMS/TRADE NAMES :
* Card-20(22)-enolide, 3,14,16-trihydroxy-, (3-beta,5-beta,16-beta)-
* Cardogenen-(20:22)-triol-(3-beta,14,16)
* Delta(20,22)-2,14,16,21-tetrahydroxynorcholenic acid lactone
* Gitoxigenin
* 16-beta-Hydroxydigitoxigenin
* 3-beta,14,16-Trioxycarden-(20:22)-olid
* 3-beta,14,16-Trioxy-digen-(20:22)-olid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 3 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC)
V.1-5, 1959-62. For publisher information, see JMCMAR.
Volume(issue)/page/year: 5,988,1962
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Bird - pigeon
DOSE/DURATION : 5400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA,
1255 Howard St., San Francisco, CA 94103) V.6- 1958-
Volume(issue)/page/year: 8,18,1960
*** REVIEWS ***
TOXICOLOGY REVIEW
85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster,
Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year:
-,191,1963
*** END OF RECORD ***