*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : FI0330000 CHEMICAL NAME : beta-Carotene-4,4'-dione, all-trans- CAS REGISTRY NUMBER : 514-78-3 BEILSTEIN REFERENCE NO. : 1898520 REFERENCE : 4-07-00-02680 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C40-H52-O2 MOLECULAR WEIGHT : 564.92 COMPOUND DESCRIPTOR : Human SYNONYMS/TRADE NAMES : * Cantaxanthin * Canthaxanthin * Canthaxanthine * Carophyll Red * all-trans,beta-Carotene-4,4'-dione * beta,beta-Carotene-4,4'-dione * C.I. Food Orange 8 * E 161 G * L-Orange 7 * Orobronze * Roxanthin Red 10 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 86 mg/kg/15W-I TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - retinal changes (pigmentary depositions, retinitis, other) REFERENCE : MJAUAJ Medical Journal of Australia. (Australasian Medical Pub. Co. Ltd., 71-79 Arundel St., Glebe, N.S.W., Australia) V.1- 1914- Volume(issue)/page/year: 143,622,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 47,39,1979 *** END OF RECORD ***