*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FL7025000
CHEMICAL NAME           : Chalcone,
                          3,4-dimethoxy-alpha-phenyl-4'-(2-(1-pyrrolidinyl)etho
                          xy)-
CAS REGISTRY NUMBER     : 15272-66-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C29-H31-N-O4
MOLECULAR WEIGHT        : 457.61
WISWESSER LINE NOTATION : T5NTJ A2OR DVYR&U1R CO1 DO1
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Acrylophenone,  
   3-(3,4-dimethoxyphenyl)-2-phenyl-4'-(2-(1-pyrrolidinyl)ethoxy)-
   * 3-(3,4-Dimethoxyphenyl)-2-phenyl-4'-beta-pyrrolidinoethoxyacrylophenone
   *   3-(3,4-Dimethoxyphenyl)-2-phenyl-4'-(2-(1-pyrrolidinyl)ethoxy)acrylophen
     one
   * 3,4-Dimethoxy-alpha-phenyl-4'-(2-(1-pyrrolidinyl)ethoxy)chalcone
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1-5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 5,169,1967
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 mg/kg
SEX/DURATION            : female 1-5 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   IJPAAO Indian Journal of Pharmacy.  (Bombay, India)  V.1-40(1), 1939-78. For
   publisher information, see IJSIDW.  Volume(issue)/page/year: 31,49,1969
 
                            *** END OF RECORD ***