*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FL7560000
CHEMICAL NAME           : Chaulmoogra oil
CAS REGISTRY NUMBER     : 8001-74-9
LAST UPDATED            : 199112
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Gynocardia oil
   * Hydnocarpus oil
   * Oils, chaulmoogra
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases.
   (POB 1097, Bloomfield, NJ 07003)  V.1-    1933-  Volume(issue)/page/year:
   5,159,1937
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 4300 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 24,221,1925
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Kidney, Ureter, Bladder - proteinuria
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 24,221,1925
 
                            *** END OF RECORD ***