*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : FM3375000 CHEMICAL NAME : Chikusetsusaponin V CAS REGISTRY NUMBER : 34367-04-9 LAST UPDATED : 199209 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C48-H76-O19 MOLECULAR WEIGHT : 957.24 COMPOUND DESCRIPTOR : Drug Natural Product SYNONYMS/TRADE NAMES : * Chikusetsusaponin 5 * Ginsenoside Ro *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 656 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 25,1017,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 278 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 25,1017,1977 *** END OF RECORD ***