*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : FO0525000
CHEMICAL NAME : Chloric acid, sodium salt
CAS REGISTRY NUMBER : 7775-09-9
OTHER CAS REGISTRY NOS. : 11096-45-0
LAST UPDATED : 199712
DATA ITEMS CITED : 27
MOLECULAR FORMULA : Cl-O3.Na
MOLECULAR WEIGHT : 106.44
WISWESSER LINE NOTATION : NA G-O3
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Mutagen
Human
Primary Irritant
SYNONYMS/TRADE NAMES :
* Agrosan
* Asex
* Atlacide
* Atratol
* B-Herbatox
* Chlorate de sodium
* Chlorate salt of sodium
* Desolet
* Drexel defol
* Evau-super
* Grain sorghum harvest-aid
* Granex O
* Harvest-aid
* Hibar C
* Kusa-tohru
* Kusatol
* Leafex 2
* Natriumchloraat
* Natriumchlorat
* Ortho C-1 defoliant & weed killer
* Oxycil
* Rasikal
* Shed-A-leaf
* Soda chlorate
* Sodakem
* Sodio (clorato di)
* Sodium chlorate
* Sodium(chlorate de)
* Travex
* Tumbleaf
* United Chemical Defoliant No. 1
* VAL-DROP
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 24-3/1971
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 10 mg
REACTION SEVERITY : Mild
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 24-3/1971
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 800 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Blood - other hemolysis with or without anemia
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
Academic Press, Inc., 1969 Volume(issue)/page/year: -,539,1969
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - man
DOSE/DURATION : 286 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cyanosis
Blood - changes in cell count (unspecified)
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher
information, see JTCTDW. Volume(issue)/page/year: 15,185,1979
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human
DOSE/DURATION : 214 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada,
171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,461,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human - child
DOSE/DURATION : 185 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada,
171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,461,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHJOAV Pharmaceutical Journal. (Pharmaceutical Soc. of Great Britain, 1
Lambeth High St., London, SE1 7JN, UK) V.131- 1933-
Volume(issue)/page/year: 185,361,1960
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >28 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 24-3/1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 8350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UZBZAZ Uzbekskii Biologicheskii Zhurnal. Uzbek Biological Journal. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1958-
Volume(issue)/page/year: (1),40,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 596 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
(Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV.
Volume(issue)/page/year: 257,791,1963
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 1350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCOC** Pesticide Chemicals Official Compendium, Association of the American
Pesticide Control Officials, Inc., 1966. (Topeka, KS)
Volume(issue)/page/year: -,1013,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 7200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 31(1),49,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 24-3/1971
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 495 mg/kg/1Y-C
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells
Blood - changes in erythrocyte (RBC) count
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JEPOEC Journal of Environmental Pathology, Toxicology and Oncology.
(Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984-
Volume(issue)/page/year: 6(1),105,1985
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 58819 mg/kg/13W-C
TOXIC EFFECTS :
Brain and Coverings - changes in brain weight
Endocrine - other changes
Blood - changes in erythrocyte (RBC) count
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New
York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 18,185,1995
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 1630 mg/kg/5D-I
TOXIC EFFECTS :
Behavioral - food intake (animal)
Blood - changes in leukocyte (WBC) count
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888-
Volume(issue)/page/year: 90,416,1972
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 40 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 90,91,1981
TYPE OF TEST : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Insect - Drosophila melanogaster
DOSE/DURATION : 250 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 90,91,1981
TYPE OF TEST : DNA inhibition
ROUTE OF EXPOSURE : Oral
TEST SYSTEM : Rodent - rat
DOSE/DURATION : 84 mg/kg/12W (Continuous)
REFERENCE :
JEPOEC Journal of Environmental Pathology, Toxicology and Oncology.
(Chem-Orbital, POB 134, Park Forest, IL 60466) V.5(4)- 1984-
Volume(issue)/page/year: 6(1),105,1985
*** REVIEWS ***
TOXICOLOGY REVIEW
JAVMA4 Journal of the American Veterinary Medical Association. (American
Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48-
1915- Volume(issue)/page/year: 164,277,1974
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 68870
No. of Facilities: 334 (estimated)
No. of Industries: 15
No. of Occupations: 14
No. of Employees: 3058 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 68870
No. of Facilities: 1023 (estimated)
No. of Industries: 35
No. of Occupations: 34
No. of Employees: 28583 (estimated)
No. of Female Employees: 5207 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NTP Carcinogenesis studies; selected, October 1997
*** END OF RECORD ***