*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : FZ3430000
CHEMICAL NAME : Cholanthrene-7,8-diol, 7,8-dihydro-3-methyl-, (E)-
CAS REGISTRY NUMBER : 68688-86-8
LAST UPDATED : 199410
DATA ITEMS CITED : 7
MOLECULAR FORMULA : C21-H18-O2
MOLECULAR WEIGHT : 302.39
WISWESSER LINE NOTATION : L E6 D6656 1A T HUT&&T&J FQ GQ R1
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* Benz(j)aceanthrylene-7,8-diol, 1,2,7,8-tetrahydro-3-methyl-, trans-
* trans-7,8-Dihydro-7,8-dihydroxy-3-methylcholanthrene
* trans-3-Methyl-7,8-dihydrocholanthrene-7,8-diol
*** HEALTH HAZARD DATA ***
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 10 umol/L
REFERENCE :
BBRCA9 Biochemical and Biophysical Research Communications. (Academic
Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year: 85,1568,1978
TYPE OF TEST : Morphological transformation
TEST SYSTEM : Rodent - mouse Fibroblast
DOSE/DURATION : 250 ug/L
REFERENCE :
BBRCA9 Biochemical and Biophysical Research Communications. (Academic
Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year: 85,1568,1978
TYPE OF TEST : Sister chromatid exchange
TEST SYSTEM : Rodent - hamster Ovary
DOSE/DURATION : 500 ug/L
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year:
7,45,1979
TYPE OF TEST : Mutation in mammalian somatic cells
TEST SYSTEM : Rodent - hamster Lung
DOSE/DURATION : 500 ug/L
REFERENCE :
BBRCA9 Biochemical and Biophysical Research Communications. (Academic
Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
Volume(issue)/page/year: 85,1568,1978
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
EPA GENETOX PROGRAM 1988, Positive: V79 cell culture-gene mutation
EPA GENETOX PROGRAM 1988, Inconclusive: Carcinogenicity-mouse/rat
*** END OF RECORD ***