*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FZ8100000
CHEMICAL NAME           : Cholest-4-en-3-one, 6-beta-hydroperoxy-
CAS REGISTRY NUMBER     : 2207-76-3
LAST UPDATED            : 199307
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C27-H44-O3
MOLECULAR WEIGHT        : 416.71
WISWESSER LINE NOTATION : L E5 B666 OV MUTJ A1 E1 FY1&3Y1&1 LOQ
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 6-Hydroperoxy-4-cholesten-3-one
   * 6-beta-Hydroperoxycholest-4-en-3-one
   * 6-beta-Hydroperoxy-delta(sup 4)-cholesten-3-one
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg/9W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   19,977,1957
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg/W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   JCSOA9 Journal of the Chemical Society.  (London, UK)  1926-65.  For
   publisher information, see JCPRB4.  Volume(issue)/page/year: 77,3928,1955
 
                            *** END OF RECORD ***