*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GA4355000
CHEMICAL NAME           : Choline, iodide, benzilate
CAS REGISTRY NUMBER     : 2424-71-7
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H24-N-O3.I
MOLECULAR WEIGHT        : 441.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzilic acid dimethylaminoethyl ester iodomethylate
   * Ethanaminium, 2-((hydroxydiphenylacetyl)oxy)-N,N,N-trimethyl-, iodide
   * Metacin
   * Metatsin
   * Methacin (anticholinergic)
   * Metocinium iodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 149 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   22,214,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 145 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 27,675,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 294 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHTXA6 Pharmacology and Toxicology.  English translation of FATOAO.  (New
   York, NY)  V.20-22, 1957-59.  Discontinued.  Volume(issue)/page/year:
   22,214,1959
 
                            *** END OF RECORD ***