*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GA7457000
CHEMICAL NAME           : Choline, compd. with 6-thiotheophylline (1:1)
LAST UPDATED            : 198511
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H7-N4-O-S.C5-H14-N-O
MOLECULAR WEIGHT        : 299.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Choline 6-thiotheophyllinate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 16,59,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 16,59,1961
 
                            *** END OF RECORD ***