*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GB4000000
CHEMICAL NAME           : Chromite (mineral)
CAS REGISTRY NUMBER     : 1308-31-2
OTHER CAS REGISTRY NOS. : 61026-56-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 28
MOLECULAR FORMULA       : Cr2-Fe-O4
MOLECULAR WEIGHT        : 223.85
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Chrome ore
   * Chromite
   * Chromite ore
   * Iron chromite
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2 mg/plate
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 2,283,1981
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 2 mg/plate
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 3,1331,1982
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 500 mg/L
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   44,219,1981
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 500 mg/L
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   44,219,1981
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - hamster Kidney
DOSE/DURATION           : 500 mg/L
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   44,219,1981
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - hamster Kidney
DOSE/DURATION           : 500 mg/L
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   44,219,1981
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 5 mg/L
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   44,219,1981
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 10 mg/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 3,1331,1982

                              *** REVIEWS ***
 
   ACGIH TLV-Confirmed human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.05 mg(Cr)/m3 (ore processing)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 23,205,1980

   IARC Cancer Review:Animal Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 49,49,1990

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 23,205,1980

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 49,49,1990

   IARC Cancer Review:Group 3
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 49,49,1990

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.5 mg(Cr)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,35,1971

   OSHA PEL (Gen Indu):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-RUSSIA:TWA 0.05 mg/m3;Carcinogen JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M2761
       No. of Facilities: 76 (estimated)
       No. of Industries: 4
       No. of Occupations: 18
       No. of Employees: 7386 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M2761
       No. of Facilities: 569 (estimated)
       No. of Industries: 5
       No. of Occupations: 13
       No. of Employees: 12920 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NTP 7th Annual Report on Carcinogens, 1992 : known to be carcinogenic

 
                            *** END OF RECORD ***