*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD2901000
CHEMICAL NAME           : Cinchonan-1-ium, 1-ethyl-9-hydroxy-, iodide, (9S)-
CAS REGISTRY NUMBER     : 73803-49-3
LAST UPDATED            : 199209
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H27-N2-O.I
MOLECULAR WEIGHT        : 450.40
WISWESSER LINE NOTATION : T66 BNJ EYQ- DT66 A B CKTJ A1U1 C2 &I  9S
SYNONYMS/TRADE NAMES :
   * Cinchonine ethiodide
   * (9S)-9-Hydroxy-1-ethylcinchonan-1-ium iodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,127,1947
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,127,1947
 
                            *** END OF RECORD ***