*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD2903000
CHEMICAL NAME           : Cinchonan-1-ium, 1-ethyl-9-hydroxy-6'-methoxy-,
                          iodide, (9S)-
CAS REGISTRY NUMBER     : 73804-26-9
LAST UPDATED            : 199209
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H29-N2-O2.I
MOLECULAR WEIGHT        : 480.43
WISWESSER LINE NOTATION : T66 BNJ HO1 EYQ- DT66 A B CKTJ A1U1 C2 &I  9S
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ethylquinidinium, iodide
   * N-Ethylquinidinium iodide
   * (9S)-9-Hydroxy-6'-methoxy-1-ethylcinchonan-1-ium iodide
   * Quinidine ethiodide
   * Quinidinium, ethyl-, iodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,127,1947
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,127,1947
 
                            *** END OF RECORD ***