*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GD2905000
CHEMICAL NAME : Cinchonan-1-ium, 9-hydroxy-6'-methoxy-1-methyl-,
iodide, (9S)-
CAS REGISTRY NUMBER : 42982-87-6
LAST UPDATED : 199209
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C21-H27-N2-O2.I
MOLECULAR WEIGHT : 466.40
WISWESSER LINE NOTATION : T66 BNJ HO1 EYQ- DT66 A B CKTJ A1U1 C1 &I 9S
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Cinchonanium, 9-hydroxy-6'-methoxy-, iodide, (9S)-
* (9S)-9-Hydroxy-6'-methoxycinchonanium iodide
* (9S)-9-Hydroxy-6'-methoxy-1-methylcinchonan-1-ium iodide
* Methylquinidinium, iodide
* 1-Methylquinidinium iodide
* Quinidine methiodide
* Quinidine-alpha-methiodide
* Quinidinium, methyl-, iodide
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 13 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Behavioral - changes in motor activity (specific assay)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 91,127,1947
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3500 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Behavioral - changes in motor activity (specific assay)
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 91,127,1947
*** END OF RECORD ***