*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD2906000
CHEMICAL NAME           : Cinchonan-1-ium, 9-hydroxy-1-methyl-, iodide,
                          (8-alpha,9R)-
CAS REGISTRY NUMBER     : 73804-27-0
LAST UPDATED            : 199209
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H25-N2-O.I
MOLECULAR WEIGHT        : 436.37
WISWESSER LINE NOTATION : T66 BNJ EYQ- DT66 A B CKTJ A1U1 C1 &I  8-ALPHA,9R
SYNONYMS/TRADE NAMES :
   * Cinchonidine methiodide
   * (8-alpha,9R)-9-Hydroxy-1-methylcinchonan-1-ium iodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,127,1947
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4500 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,127,1947
 
                            *** END OF RECORD ***