*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD2975000
CHEMICAL NAME           : Cinchonidine
CAS REGISTRY NUMBER     : 485-71-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H22-N2-O
MOLECULAR WEIGHT        : 294.43
WISWESSER LINE NOTATION : T66 BNJ EYQ- DT66 A B CNTJ A1U1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Cinchonan-9-ol, (8-alpha,9R)-
   * (-)-Cinchonidine
   * (8S,9R)-Cinchonidine
   * Cinchovatine
   * alpha-Quinidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 206 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   4,265,1948
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : >316 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EESADV Ecotoxicology and Environmental Safety.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1977-  Volume(issue)/page/year:
   6,149,1982

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***