*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD6476000
CHEMICAL NAME           : Cinnamaldehyde, (E)-
CAS REGISTRY NUMBER     : 14371-10-9
BEILSTEIN REFERENCE NO. : 1071571
REFERENCE               : 4-07-00-00984 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C9-H8-O
MOLECULAR WEIGHT        : 132.17
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * (E)-Cinnamaldehyde
   * trans-Cinnamaldehyde
   * trans-Cinnamic aldehyde
   * trans-Cinnamylaldehyde
   * (E)-3-Phenylpropenal
   * (E)-3-Phenyl-2-propenal
   * 2-Propenal, 3-phenyl-, (E)-
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 322,1,1994
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 850 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 322,1,1994
 
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 10 nmol/L
REFERENCE :
   JTSCDR Journal of Toxicological Sciences.  (Japanese Soc. of Toxicological
   Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
   Tokyo 113, Japan)  V.1-    1976-  Volume(issue)/page/year: 10,177,1985
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 2 nmol/L
REFERENCE :
   JTSCDR Journal of Toxicological Sciences.  (Japanese Soc. of Toxicological
   Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
   Tokyo 113, Japan)  V.1-    1976-  Volume(issue)/page/year: 10,177,1985
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 340 ug/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

                          *** STATUS IN U.S. ***
 
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NTP Carcinogenesis studies; on test (two year studies), October 1997

 
                            *** END OF RECORD ***