*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : GD9275000 CHEMICAL NAME : Cinnamic acid, 4-hydroxy-3-methoxy-, (E)- CAS REGISTRY NUMBER : 537-98-4 LAST UPDATED : 199709 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C10-H10-O4 MOLECULAR WEIGHT : 194.20 WISWESSER LINE NOTATION : QV1U1R DQ CO1 -T COMPOUND DESCRIPTOR : Mutagen Reproductive Effector SYNONYMS/TRADE NAMES : * Cinnamic acid, 4-hydroxy-3-methoxy-, trans- * Ferulic acid, trans- * (E)-Ferulic acid * trans-4-Hydroxy-3-methoxycinnamic acid * (E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid * 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (E)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >194 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 104,793,1984 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,688,1955 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE : 9600 mg/kg SEX/DURATION : female 12 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 195,575,1977 ** MUTATION DATA ** TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 25 gm/L REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 14,251,1981 *** END OF RECORD ***