*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GB7881000
CHEMICAL NAME           : Chromomycinone,
                          6-(2,6-dideoxy-4-O-(2,6-dideoxy-4-O-methyl-D-lyxo-hex
                          opyranosyl)-D-lyxo- hexopyranoside)
                          2-(O-2,6-dideoxy-3-C-methyl-L-arabino-hexopyranosyl-(
                          1-3)-O-2,6-dideoxy-D-
                          arabino-hexopyranosyl-(1-3)-2,6-dideoxy-D-arabino-hex
                          opyranoside), monoacetate, isobutyrate
CAS REGISTRY NUMBER     : 6992-70-7
LAST UPDATED            : 198804
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C59-H86-O26
MOLECULAR WEIGHT        : 1211.45
WISWESSER LINE NOTATION : L C666 DVT&&J BQ FYO1&VYQYQ1 M1 NQ LO- FT6OTJ B1 DOV1
                          CO- FT6OTJ B1 CO1 DQ&& EO- FT6OTJ B1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Aburamycin A
   * Chromomycin A2
   * Chromomycin A(sub 2)
   * NSC 131187
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 241 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,215,1967
 
                            *** END OF RECORD ***