*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GB7898100
CHEMICAL NAME           : Chromone-2-carboxylic acid,
                          7-hydroxy-8-(4-methylpiperazin-1-ylmethyl)-, ethyl
                          ester, dihydrochloride
CAS REGISTRY NUMBER     : 53708-73-9
LAST UPDATED            : 199409
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H22-N2-O5.2Cl-H
MOLECULAR WEIGHT        : 419.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Hydroxy-8-(4-methylpiperazin-1-ylmethyl)chromone-2-carboxylic acid  
   ethyl ester 2HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 8,337,1974
 
                            *** END OF RECORD ***