*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GE6650000
CHEMICAL NAME           : Citraconic acid
CAS REGISTRY NUMBER     : 498-23-7
BEILSTEIN REFERENCE NO. : 1722679
REFERENCE               : 4-02-00-02230 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H6-O4
MOLECULAR WEIGHT        : 130.11
WISWESSER LINE NOTATION : QVY1&U1VQ
SYNONYMS/TRADE NAMES :
   * 2-Butenedioic acid, 2-methyl-, (Z)-
   * Kyselina citrakonova
   * Maleic acid, methyl-
   * cis-Methylbutenedioic acid
   * 2-Methyl-2-butenedioic acid
   * (Z)-2-Methyl-2-butenedioic acid
   * Methylmaleic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1320 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 2,327,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2260 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Gastrointestinal - other changes
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 2,327,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1350 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 2,327,1964
 
                            *** END OF RECORD ***