*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GF9274000
CHEMICAL NAME           : Cobaltate(2-),
                          ((N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycinato))
                          (4-)-N,N',O,O',O(sup N), O(sup N'))-, cobalt(2+)
                          (1:1), (OC-6-21)
CAS REGISTRY NUMBER     : 36499-65-7
OTHER CAS REGISTRY NOS. : 71-02-3
                          12203-27-9
LAST UPDATED            : 199209
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C10-H12-Co-N2-O8.Co
MOLECULAR WEIGHT        : 406.10
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ba 2724
   * Cobaltate(2-), ((ethylenedinitrilo)tetraacetato(2-))-, cobalt(2+) salt
   * Cobalt (2)-edathamil
   * Cobalt ((ethylenedinitrilo)tetraacetato)cobaltate(II)
   * Cobaltous EDTA
   * Dicobalt edetate
   * Dicobalt EDTA
   * Dikobalt aethylendiamtetraacetat
   * EDTA cobalt salt
   * Kelocyanor
   * Kobalt-edta
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 243,254,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 143,219,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 18,55,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ATXKA8 Archiv fuer Toxikologie.  (Berlin, Fed. Rep. Ger.)  V.15-31, 1954-74.
    For publisher information, see ARTODN.  Volume(issue)/page/year:
   24,235,1969
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 560 mg/kg/14D-C
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Related to Chronic Data - death
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 243,254,1962

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO COBALT METAL, dust and fume-air:10H TWA 0.05 mg/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

 
                            *** END OF RECORD ***