*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GG8225000
CHEMICAL NAME           : Codeinone, 14-hydroxy-
CAS REGISTRY NUMBER     : 508-54-3
BEILSTEIN REFERENCE NO. : 4552573
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H19-N-O4
MOLECULAR WEIGHT        : 313.38
WISWESSER LINE NOTATION : T B6566 B6/CO 4ABBC R BX FV HO PN DU GHT&&TTJ CQ JO1
                          P1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Hydroxycodeinone
   * 14-Hydroxycodeinone
   * 14-beta-Hydroxycodeinone
   * Morphinan-6-one, 7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, 
    (5-alpha)-
   * Morphinan-6-one,  
   7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 23 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZNAE "Public Health Reports, Supplement."  (Washington, DC)
   Volume(issue)/page/year: 138,27,1938
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11800 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 16(Suppl),68T,1964
 
                            *** END OF RECORD ***