*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GM7915000
CHEMICAL NAME           : alpha(sup 1-24)-Corticotropin
CAS REGISTRY NUMBER     : 16960-16-0
BEILSTEIN REFERENCE NO. : 0940671
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C136-H210-N40-O31-S
MOLECULAR WEIGHT        : 2933.92
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Acth(sup 1-24)
   * ACTH-alpha(sup 1-24)
   * alpha(sup 1-24)-Acth
   * beta(sup 1-24)-Acth
   * Actholain
   * Ba 30920
   * Ba 36716
   * Corticotropin-(1-24)
   * beta-1,24-Corticotrophin
   * beta(sup 1-24)-Corticotropin
   * Cortrophin S
   * Cortrosinta
   * Cortrosyn
   * Cosyntropin
   * Nuvacthen depot
   * Synacthen
   * Tetracosactid
   * Tetracosactide
   * beta(sup 1-24)-Tetracosactide
   * Tetracosactrin
   * Tetracosapeptide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 5 ug/kg
TOXIC EFFECTS :
   Cardiac - change in rate
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JAMAAP JAMA, Journal of the American Medical Association.  (AMA, 535 N.
   Dearborn St., Chicago, IL 60610)  V.1-    1883-  Volume(issue)/page/year:
   237,879,1977

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4549
       No. of Facilities: 24 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 1071 (estimated)
       No. of Female Employees: 546 (estimated)

 
                            *** END OF RECORD ***