*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GM9002500
CHEMICAL NAME           : Cortisol, 21-butyrate
CAS REGISTRY NUMBER     : 6677-99-2
LAST UPDATED            : 198610
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H36-O6
MOLECULAR WEIGHT        : 432.61
WISWESSER LINE NOTATION : L E5 B666 OV MUTJ A1 CQ E1 FV1OV3 FQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * HB(sub 21)
   * Hydrocortisone-21-butyrate
   * Pregn-4-en-3,20-dione, 11,17-dihydroxy-21-(1-oxobutoxy)-, (11-beta)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2070 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JTSCDR Journal of Toxicological Sciences.  (Japanese Soc. of Toxicological
   Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
   Tokyo 113, Japan)  V.1-    1976-  Volume(issue)/page/year: 6(Suppl 1),1,1981
 
                            *** END OF RECORD ***