*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN1925500
CHEMICAL NAME           : Cotinine
CAS REGISTRY NUMBER     : 486-56-6
BEILSTEIN REFERENCE NO. : 0083099
REFERENCE               : 5-24-02-00504 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-N2-O
MOLECULAR WEIGHT        : 176.24
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (-)-Cotinine
   * (S)-Cotinine
   * (S)-1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
   * NIH 10498
   * 2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-, (S)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1604 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 137,313,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 930 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 137,313,1962
 
                            *** END OF RECORD ***