*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GN5250000
CHEMICAL NAME : Coumarin, 3-chloro-7-hydroxy-4-methyl-,
bis(2-chloroethyl) phosphate
CAS REGISTRY NUMBER : 321-55-1
BEILSTEIN REFERENCE NO. : 1271357
LAST UPDATED : 199612
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C14-H14-Cl3-O6-P
MOLECULAR WEIGHT : 415.60
WISWESSER LINE NOTATION : T66 BOVJ DG E1 IOPO&O2GO2G
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
SYNONYMS/TRADE NAMES :
* O,O-Bis(2-chloroethyl) O-(3-chloro-4-methyl-7-coumarinyl) phosphate
* 3-Chloro-7-hydroxy-4-methylcoumarin bis(2-chloroethyl)phosphate
* 3-Chloro-4-methyl-umbelliferone bis(2-chloroethyl)phosphate
* Di-(2-chloroethyl)-3-chloro-4-methyl-7-coumarinyl phosphate
* Di-(2-chloroethyl) 3-chloro-4-methylcoumarin-7-yl phosphate
* O,O-Di(2-chloroethyl)-O-(3-chloro-4-methylcoumarin-7-yl)phosphate
* Ethanol, 2-chloro-, hydrogen phosphate, ester with
3-chloro-7-hydroxy-4-methylcoumarin
* Ethanol, 2-chloro-, phosphate diester, ester with
3-chloro-7-hydroxy-4-methylcoumarin
* Eustidil
* Galloxon
* Galoxane
* Galoxone
* 96H60
* Haloxon
* Helmirane
* Helmiron
* Helmirone
* Loxon
* Luxon
* LXON
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research.
(Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 17,108,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71.
Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : >7 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
16,1183,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
16,1183,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - domestic
DOSE/DURATION : 763 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - food intake (animal)
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
AJVRAH American Journal of Veterinary Research. (American Veterinary
Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940-
Volume(issue)/page/year: 41,1857,1980
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Human Cells - not otherwise specified
DOSE/DURATION : 10 mg/L
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 10,143,1982
*** REVIEWS ***
TOXICOLOGY REVIEW
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44
Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year:
46,1,1973
TOXICOLOGY REVIEW
PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52
Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year:
10,85,1974
*** END OF RECORD ***