*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN6370000
CHEMICAL NAME           : Coumarin, 7-diethylamino-4-methyl-
CAS REGISTRY NUMBER     : 91-44-1
BEILSTEIN REFERENCE NO. : 0193303
REFERENCE               : 5-18-11-00445 (Beilstein Handbook Reference)
LAST UPDATED            : 199803
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C14-H17-N-O2
MOLECULAR WEIGHT        : 231.32
WISWESSER LINE NOTATION : T66 BOVJ E1 IN2&2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aclarat 8678
   * 2H-1-Benzopyran-2-one, 7-(diethylamino)-4-methyl-
   * Blancophor AW
   * Blancophor FFG
   * C 47
   * Calcofluor White RW
   * Calcofluor White SD
   * Coumarin 1
   * Coumarin 47
   * Coumarin 460
   * 7-(Diethylamino)-4-methyl-2H-1-benzopyran-2-one
   * 7-Diethylamino-4-methylcoumarin
   * 7-Diethylamino-4-methylcumarin
   * 7D4MC
   * Hakkol P
   * Hiltamine Artic White SOL
   * MDAC
   * Uvitex WGS
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MVCRB3 MVC-Report.  (Stockholm, Sweden)  No.1-2, 1972-73.  Discontinued.
   Volume(issue)/page/year: 2,193,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1780 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   SRTCAC Science Reports of the Research Institutes, Tohoku University, Series
   C: Medicine. (Tohoku University, Research Institute for Tuberculosis and
   Cancer, 4-1 Seiryo-machi, Sendai, Japan)  V.1-   1949-
   Volume(issue)/page/year: 36(1-4),10,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#03230

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X9410
       No. of Facilities: 1470 (estimated)
       No. of Industries: 11
       No. of Occupations: 18
       No. of Employees: 21642 (estimated)
       No. of Female Employees: 8996 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***