*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN6384500
CHEMICAL NAME           : Coumarin, 6,7-dihydroxy-4-methyl-
CAS REGISTRY NUMBER     : 529-84-0
BEILSTEIN REFERENCE NO. : 0162550
REFERENCE               : 5-18-03-00231 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H8-O4
MOLECULAR WEIGHT        : 192.18
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2H-1-Benzopyran-2-one, 6,7-dihydroxy-4-methyl-
   * 6,7-Dihydroxy-4-methyl-2H-1-benzopyran-2-one
   * 6,7-Dihydroxy-4-methylcoumarin
   * 4-Methylaesculetin
   * Methylesculetin
   * 4-Methylesculetin
   * 4-Methylesculetol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5130 mg/kg
TOXIC EFFECTS :
   Cardiac - arrhythmias (including changes in conduction)
   Cardiac - cardiomegaly
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 20,879,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MPHEAE Medicina et Pharmacologia Experimentalis.  (Basel, Switzerland)
   V.12-17, 1965-67.  For publisher information, see PHMGBN.
   Volume(issue)/page/year: 17,497,1967

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***