*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN7546000
CHEMICAL NAME           : Coumarin,
                          7-hydroxy-4-methyl-8-(piperidinomethyl)-4-methyl-,
                          isonicotinate (salt)
CAS REGISTRY NUMBER     : 10550-22-8
LAST UPDATED            : 198306
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H19-N-O3.C6-H5-N-O2
MOLECULAR WEIGHT        : 396.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Hydroxy-4-methyl-8-(piperidinomethyl)-4-methylcoumarin isonicotinate  
   (salt)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 1,403,1966
 
                            *** END OF RECORD ***