*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GO7300100
CHEMICAL NAME           : o-Cresol,
                          4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 69-44-3
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H22-Cl-N3-O.2Cl-H
MOLECULAR WEIGHT        : 428.82
WISWESSER LINE NOTATION : T66 BNJ IG EMR DQ C1N2&2 &GH 2
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Amodiaquin dihydrochloride
   * Camoquin hydrochloride
   * 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol  
   dihydrochloride
   * Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-,  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 52 mg/kg/13W-I
TOXIC EFFECTS :
   Blood - agranulocytosis
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   292,717,1986
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 137 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,1471,1981
 
                            *** END OF RECORD ***