*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : GO7300100 CHEMICAL NAME : o-Cresol, 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-, dihydrochloride CAS REGISTRY NUMBER : 69-44-3 LAST UPDATED : 199707 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H22-Cl-N3-O.2Cl-H MOLECULAR WEIGHT : 428.82 WISWESSER LINE NOTATION : T66 BNJ IG EMR DQ C1N2&2 &GH 2 COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Amodiaquin dihydrochloride * Camoquin hydrochloride * 4-((7-Chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol dihydrochloride * Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-, dihydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 52 mg/kg/13W-I TOXIC EFFECTS : Blood - agranulocytosis REFERENCE : BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 292,717,1986 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 137 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,1471,1981 *** END OF RECORD ***