*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GQ5600000
CHEMICAL NAME           : Crotonic acid, 3-methyl-,
                          2-sec-butyl-4,6-dinitrophenyl ester
CAS REGISTRY NUMBER     : 485-31-4
BEILSTEIN REFERENCE NO. : 2013712
LAST UPDATED            : 199612
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C15-H18-N2-O6
MOLECULAR WEIGHT        : 322.35
WISWESSER LINE NOTATION : 2Y1&R CNW ENW BOV1UY1&1
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acricid
   * Ambox
   * Binapacryl
   * 2-Butenoic acid, 3-methyl-, 2-(1-methylpropyl)-4,6-dinitrophenyl ester
   * 2-sek.Butyl-4,6-dinitrofenylester kyseliny 3-methylkrotonove
   * 2-sec-Butyl-4,6-dinitrophenyl-3,3-dimethylacrylate
   * 2-sec-Butyl-4,6-dinitrophenyl 3-methyl-2-butenoate
   * 2-sec-Butyl-4,6-dinitrophenyl 3-methylcrotonate
   * 2-sec-Butyl-4,6-dinitrophenyl senecioate
   * Dapacryl
   * 3,3 Dimethyl-acrylate de 2,4-dinitro-6-(1-methylpropyle) phenyle
   * 3,3-Dimethylacrylic acid 2-sec-butyl-4,6-dinitrophenyl ester
   * Dinapacryl
   * 4,6-Dinitro-2-sec-butylphenyl beta,beta-dimethylacrylate
   * 2,4-Dinitro-6-sec-butylphenyl 2-methylcrotonate
   * 4,6-Dinitrophenyl-2-sec-butyl-3-methyl-2-butenonate
   * Dinoseb, 3,3-dimethylacryl ester
   * Dinoseb methacrylate
   * Endosan
   * ENT 25,793
   * FMC 9044
   * HOE 2784
   * HOE 2784 OA
   * 3-Methyl-2-butenoic acid 2-sec-butyl-4,6-dinitrophenyl ester
   * 3-Methyl-2-butenoic acid 2-(1-methylpropyl)-4,6-dinitrophenyl ester
   * 3-Methylcrotonic acid 2-sec-butyl-4,6-dinitrophenyl ester
   * (6-(1-Methyl-propyl)-2,4-dinitro-fenyl)-3,3-dimethyl-acrylaat
   * 2-(1-Methylpropyl)-4,6-dinitrophenyl beta,beta-dimethacrylate
   * (6-(1-Methyl-propyl)-2,4-dinitro-phenyl)-3,3-dimethyl-acrylat
   * (6-(1-Metil-propil)-2,4-dinitro-fenil)-3,3-dimetil-acrilato
   * Morocide
   * Morrocid
   * NIA 9044
   * Niagara 9044
   * Phenol, 2-sec-butyl-4,6-dinitro-, 3-methylcrotonate
   * Senecioic acid 2-sec butyl-4,6-dinitrophenyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,515,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 720 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 9,119,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   7,353,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   8,73,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,42,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,42,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   7,353,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : >800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   7,353,1965
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 mg/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 116,185,1983
 
                            *** END OF RECORD ***