*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GQ5783000
CHEMICAL NAME           : Crotonic acid, 3-methyl-,
                          1-methyl-4-phenyl-4-piperidyl ester, hydrochloride
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H23-N-O2.Cl-H
MOLECULAR WEIGHT        : 309.87
WISWESSER LINE NOTATION : T6NTJ A1 DR& DOV1UY1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-Methylcrotonic acid 2-methyl-4-phenyl-4-piperidyl ester hydrochloride
   * 1-Methyl-4-phenyl-4-beta,beta-dimethylacroyloxypiperidine hydrochloride
   * NU-857
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 227 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,195,1947
 
                            *** END OF RECORD ***