*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GQ5805000
CHEMICAL NAME           : Crotonic acid, 1,4-piperazinylenediethylene ester,
                          dihydrochloride
LAST UPDATED            : 198312
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H26-N2-O4.2Cl-H
MOLECULAR WEIGHT        : 383.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,4-Piperazinediethanol, dicrotonate (ester), dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
   Behavioral - analgesia
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 55,290,1966
 
                            *** END OF RECORD ***