*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : GP3920000 CHEMICAL NAME : 2,3-Cresotic acid CAS REGISTRY NUMBER : 83-40-9 BEILSTEIN REFERENCE NO. : 2086811 REFERENCE : 4-10-00-00601 (Beilstein Handbook Reference) LAST UPDATED : 199710 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C8-H8-O3 MOLECULAR WEIGHT : 152.16 WISWESSER LINE NOTATION : QVR BQ C1 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * Acido ortocresotinico * Acido 3-ossi-5-metil-benzoico * Benzoic acid, 2-hydroxy-3-methyl- * Cresotic acid * o-Cresotic acid * Cresotinic acid * beta-Cresotinic acid * o-Cresotinic acid * 2,3-Cresotinic acid * Homosalicylic acid * 2-Hydroxy-3-methylbenzoic acid * 3-Methylsalicylic acid * 3-MS *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 445 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BIALAY Biochimica Applicata. (Parma, Italy) V.1-19, 1954-72(?). Discontinued. Volume(issue)/page/year: 10,270,1963 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 7,289,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 345 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 20,506,1965 ** MUTATION DATA ** TYPE OF TEST : DNA inhibition TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 1 mmol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 29,1275,1980 *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA Section 8(d) unpublished health/safety studies EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***