*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU3511990
CHEMICAL NAME           : 6H-Cyclohepta(b)quinoline,
                          11-((3-(dimethylamino)propyl)thio)-7,8,9,10-tetrahydr
                          o-, dihydrochloride
CAS REGISTRY NUMBER     : 18937-25-2
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H26-N2-S.2Cl-H
MOLECULAR WEIGHT        : 387.45
WISWESSER LINE NOTATION : T C667 BN&&TJ IS3N1&1 &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   11-((3-(Dimethylamino)propyl)thio)-7,8,9,10-tetrahydro-6H-cyclohepta(b)q
     uinoline 2HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,388,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,388,1968
 
                            *** END OF RECORD ***