*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU3514700
CHEMICAL NAME           : 6H-Cyclohepta(b)quinoline,
                          7,8,9,10-tetrahydro-11-amino-2-methyl-
CAS REGISTRY NUMBER     : 5778-85-8
BEILSTEIN REFERENCE NO. : 0476169
REFERENCE               : 5-22-10-00508 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H18-N2
MOLECULAR WEIGHT        : 226.35
WISWESSER LINE NOTATION : T C667 BN&&TJ F1 IZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 11-Amino-2-methyl-7,8,9,10-tetrahydro-6H-cyclohepta(b)quinoline
   * MAS 695
   * 7,8,9,10-Tetrahydro-11-amino-2-methyl-6H-cyclohepta(b)quinoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 146,406,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Behavioral - euphoria
   Behavioral - antipsychotic
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 8,409,1974
 
                            *** END OF RECORD ***