*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU4678000
CHEMICAL NAME           : Cyclohept(b)indole,
                          5,6,7,8,9,10-hexahydro-5-(3-(dimethylamino)propyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 73806-32-3
LAST UPDATED            : 198204
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H26-N2.Cl-H
MOLECULAR WEIGHT        : 306.92
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(3-(Dimethylamino)propyl)-5,6,7,8,9,10-hexahydrocyclohept(b)indole  
   hydrochloride
   * 1-(gamma-Dimethylaminopropyl)-2,3-pentamethyleneindole, hydrochloride
   * 5,6,7,8,9,10-Hexahydro-5-(3-(dimethylamino)propyl)cyclohept(b)indole  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,313,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#07176
 
                            *** END OF RECORD ***