*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU8582800
CHEMICAL NAME           : Cyclohexanecarboxylic acid, 2-hydroxy-2-phenyl-, cis-
CAS REGISTRY NUMBER     : 57808-63-6
LAST UPDATED            : 198706
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C13-H16-O3
MOLECULAR WEIGHT        : 220.29
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cicloxilic acid
   * Cicloxilico acido
   * Cycloxilic acid
   * cis-2-Hidroxi-2-fenilciclohexanocarboxilico acido
   * cis-2-Hydroxy-2-phenylcyclohexanecarboxylic acid
   * Plecton
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1570 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BraG## Personal Communication from G. Bramanti, Research Director,
   Laboratorio Guidotti SpA, Via Trieste 40, Casella Postale 236, 56100 Pisa,
   Italy, Nov. 25, 1986  Volume(issue)/page/year: 25NOV1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1040 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BraG## Personal Communication from G. Bramanti, Research Director,
   Laboratorio Guidotti SpA, Via Trieste 40, Casella Postale 236, 56100 Pisa,
   Italy, Nov. 25, 1986  Volume(issue)/page/year: 25NOV1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BraG## Personal Communication from G. Bramanti, Research Director,
   Laboratorio Guidotti SpA, Via Trieste 40, Casella Postale 236, 56100 Pisa,
   Italy, Nov. 25, 1986  Volume(issue)/page/year: 25NOV1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2095 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BraG## Personal Communication from G. Bramanti, Research Director,
   Laboratorio Guidotti SpA, Via Trieste 40, Casella Postale 236, 56100 Pisa,
   Italy, Nov. 25, 1986  Volume(issue)/page/year: 25NOV1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BraG## Personal Communication from G. Bramanti, Research Director,
   Laboratorio Guidotti SpA, Via Trieste 40, Casella Postale 236, 56100 Pisa,
   Italy, Nov. 25, 1986  Volume(issue)/page/year: 25NOV1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1860 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BraG## Personal Communication from G. Bramanti, Research Director,
   Laboratorio Guidotti SpA, Via Trieste 40, Casella Postale 236, 56100 Pisa,
   Italy, Nov. 25, 1986  Volume(issue)/page/year: 25NOV1986
 
                            *** END OF RECORD ***