*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GV2975000
CHEMICAL NAME           : Cyclohexaneglycolic acid, alpha-phenyl-,
                          1-methyl-3-piperidyl ester
CAS REGISTRY NUMBER     : 4354-45-4
BEILSTEIN REFERENCE NO. : 1437277
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H29-N-O3
MOLECULAR WEIGHT        : 331.50
WISWESSER LINE NOTATION : T6NTJ A1 COVXQR&- AL6TJ
SYNONYMS/TRADE NAMES :
   * Delinal
   * JB 840
   * N-Methyl-3-piperidyl-alpha-cyclohexyl mandelate
   * 1-Methyl-3-piperidyl alpha-phenylcyclohexaneglycolate
   * NDR 263
   * Oxyclipine
   * 3-Piperidinol, 1-methyl-, alpha-phenylcyclohexaneglycolate (ester)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,186,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Behavioral - ataxia
   Cardiac - pulse rate increase, without fall in BP
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,186,1959
 
                            *** END OF RECORD ***