*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GW0875000
CHEMICAL NAME           : Cyclohexanol, 3,3,5-trimethyl-
CAS REGISTRY NUMBER     : 116-02-9
BEILSTEIN REFERENCE NO. : 2203314
REFERENCE               : 3-06-00-00115 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : C9-H18-O
MOLECULAR WEIGHT        : 142.27
WISWESSER LINE NOTATION : L6TJ A1 A1 CQ E1
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Cyclonol
   * Homomenthol
   * Isophorol, dihydro-
   * 3,3,5-Trimethylcyclohexanol
   * 3,3,5-Trimethyl-1-cyclohexanol
   * 3,5,5-Trimethylcyclohexanol
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REACTION SEVERITY       : Moderate
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 12,1007,1974
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 20 mg/24H
REACTION SEVERITY       : Moderate
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,216,1986
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 ug
REACTION SEVERITY       : Severe
REFERENCE :
   AJOPAA American Journal of Ophthalmology.  (Ophthalmic Pub. Co., 435 N.
   Michigan Ave., Suite 1415, Chicago, IL 60611)  Series 3: V.1-    1918-
   Volume(issue)/page/year: 29,1363,1946
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 250 ug/24H
REACTION SEVERITY       : Severe
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,216,1986
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 31,60,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 31,60,1949

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1317
       No. of Facilities: 88 (estimated)
       No. of Industries: 2
       No. of Occupations: 14
       No. of Employees: 4164 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M1317
       No. of Facilities: 44 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 355 (estimated)
       No. of Female Employees: 133 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***