*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GW1750000
CHEMICAL NAME : Cyclohexanone, 2-methyl-
CAS REGISTRY NUMBER : 583-60-8
LAST UPDATED : 199712
DATA ITEMS CITED : 30
MOLECULAR FORMULA : C7-H12-O
MOLECULAR WEIGHT : 112.19
WISWESSER LINE NOTATION : L6VTJ B1
SYNONYMS/TRADE NAMES :
* 2-Methyl-cyclohexanon
* alpha-Methylcyclohexanone
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2140 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
30,470,1969
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2800 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
30,470,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD691-490
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 270 mg/kg
TOXIC EFFECTS :
Cardiac - change in rate
Vascular - BP lowering not characterized in autonomic section
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
(Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV.
Volume(issue)/page/year: 236,633,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1770 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf
Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:
30,470,1969
*** REVIEWS ***
ACGIH TLV-STEL 344 mg/m3 (75 ppm) (skin)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 229 mg/m3 (50 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 50 ppm (230 mg/m3) (skin)
DTLWS* "Documentation of the Threshold Limit Values for Substances in
Workroom Air," Supplements. For publisher information, see 85INA8.
Volume(issue)/page/year: 3,23,1973
OSHA PEL (Gen Indu):8H TWA 100 ppm (460 mg/m3) (skin)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 100 ppm (460 mg/m3) (skin)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 100 ppm (460 mg/m3) (skin)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 100 ppm (460 mg/m3) (skin)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 50 ppm (230 mg/m3);STEL 75 ppm;Skin JAN 1993
OEL-BELGIUM:TWA 50 ppm (229 mg/m3);STEL 75 ppm (344 mg/m3);Skin JAN 1993
OEL-DENMARK:TWA 50 ppm (230 mg/m3);Skin JAN 1993
OEL-FINLAND:TWA 50 ppm (230 mg/m3);STEL 75 ppm (345 mg/m3);Skin JAN 1993
OEL-FRANCE:TWA 50 ppm (230 mg/m3);Skin JAN 1993
OEL-GERMANY:TWA 50 ppm (230 mg/m3);Skin JAN 1993
OEL-JAPAN:TWA 50 ppm (230 mg/m3);Skin JAN 1993
OEL-THE NETHERLANDS:TWA 50 ppm (230 mg/m3);Skin JAN 1993
OEL-THE PHILIPPINES:TWA 100 ppm (460 mg/m3);Skin JAN 1993
OEL-RUSSIA:TWA 50 ppm JAN 1993
OEL-SWITZERLAND:TWA 50 ppm (230 mg/m3);STEL 100 ppm;Skin JAN 1993
OEL-TURKEY:TWA 100 ppm (460 mg/m3);Skin JAN 1993
OEL-UNITED KINGDOM:TWA 50 ppm (230 mg/m3);STEL 75 ppm;Skin JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO THE CHEMICAL-air:10H TWA 50 ppm (Sk);STEL 75 ppm (Sk)
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
NIOSH Analytical Method, 1994: Methylcyclohexanone, 2521
*** END OF RECORD ***