*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GW2500000
CHEMICAL NAME : Cyclohexene
CAS REGISTRY NUMBER : 110-83-8
BEILSTEIN REFERENCE NO. : 0906737
REFERENCE : 4-05-00-00218 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 34
MOLECULAR FORMULA : C6-H10
MOLECULAR WEIGHT : 82.16
WISWESSER LINE NOTATION : L6UTJ
SYNONYMS/TRADE NAMES :
* Benzenetetrahydride
* Benzene, tetrahydro-
* Cyclohexene
* Cykloheksen
* Hexanaphthylene
* Tetrahydrobenzene
* 1,2,3,4-Tetrahydrobenzene
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2400 uL/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - tremor
Behavioral - ataxia
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0546026
TYPE OF TEST : LC - Lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >6370 ppm/4H
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - ataxia
Lungs, Thorax, or Respiration - other changes
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0555329
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and
Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
V.1-36, 1957-1992. For publisher information, see MTPEEI
Volume(issue)/page/year: 29(12),53,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >3200 uL/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0546026
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 600 ppm/6H/26W-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
37,155,1976
*** REVIEWS ***
ACGIH TLV-TWA 1010 mg/m3 (300 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 300 ppm (1015 mg/m3)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,66,1971
OSHA PEL (Gen Indu):8H TWA 300 ppm (1015 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 300 ppm (1015 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 300 ppm (1015 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 300 ppm (1015 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-AUSTRIA:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-BELGIUM:TWA 300 ppm (1010 mg/m3) JAN 1993
OEL-DENMARK:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-FINLAND:TWA 300 ppm (1015 mg/m3);STEL 375 ppm (1270 mg/m3) JAN 1993
OEL-FRANCE:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-GERMANY:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-THE NETHERLANDS:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-THE PHILIPPINES:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL-POLAND:TWA 300 mg/m3 JAN 1993
OEL-RUSSIA:STEL 50 mg/m3 JAN 1993
OEL-SWITZERLAND:TWA 300 ppm (1015 mg/m3);STEL 600 ppm JAN 1993
OEL-TURKEY:TWA 300 ppm (1050 mg/m3) JAN 1993
OEL-UNITED KINGDOM:TWA 300 ppm (1015 mg/m3) JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO CYCLOHEXENE-air:10H TWA 300 ppm
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 21705
No. of Facilities: 16 (estimated)
No. of Industries: 1
No. of Occupations: 7
No. of Employees: 529 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 21705
No. of Facilities: 40 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 517 (estimated)
No. of Female Employees: 239 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
NIOSH Analytical Method, 1994: Hydrocarbons, BP 36-126 degree C, 1500
*** END OF RECORD ***