*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GW4563332
CHEMICAL NAME           : 3-Cyclohexene-1-carboxylic acid,
                          2-(methylamino)-1-phenyl-, ethyl ester,
                          monohydrochloride, trans-(+)-
CAS REGISTRY NUMBER     : 37815-45-5
LAST UPDATED            : 199703
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C16-H21-N-O2.Cl-H
MOLECULAR WEIGHT        : 295.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ethyl trans-(+)-2-(methylamino)-1-phenyl-3-cyclohexene-1-carboxylate  
   hydrochloride
   * (+)-3R-N-Monomethylamino-4c-phenyl-4t-ethoxycarbonylcyclohexene-1,  
   hydrochloride
   * (+)-Nortilidine, monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 192 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3882164
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 204 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3882164
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3882164
 
                            *** END OF RECORD ***