*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GY3850000
CHEMICAL NAME           : Cyclopentanecarboxylic acid, 1-phenyl-,
                          2-(diethylamino)ethyl ester, compd. with
                          1,2-ethanedisulfonic acid (2:1)
CAS REGISTRY NUMBER     : 125-86-0
LAST UPDATED            : 199504
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C18-H27-N-O2.1/2C2-H6-O6-S2
MOLECULAR WEIGHT        : 479.66
WISWESSER LINE NOTATION : WSQ2SWQ &622
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   Bis(1-(carbo-beta-diethylaminoethoxy)-1-phenylcyclopentane)ethanedisulfo
     nate
   *   Bis(1-(2-diethylaminoethoxycarbonyl)-1-phenylcyclopentane)ethanedisulfon
     ate
   * Caramiphen ethane disulfonate
   * Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate ethanedisulfonate
   * Parpanit ethane disulfonate
   * 1-Phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester,  
   1,2-ethanedisulfonate
   * SKF No. 769-J(sub 2)
   * Taoryl
   * Toryn
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,363,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 485 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,363,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,363,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,363,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,363,1972

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X2910
       No. of Facilities: 25 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 427 (estimated)
       No. of Female Employees: 176 (estimated)

 
                            *** END OF RECORD ***