*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GY5892000
CHEMICAL NAME           : Cyclopenta(b)pyrrol-6-ol, octahydro-1,2-dimethyl-,
                          hydriodide
CAS REGISTRY NUMBER     : 37642-31-2
LAST UPDATED            : 198806
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H17-N-O.H-I
MOLECULAR WEIGHT        : 283.18
WISWESSER LINE NOTATION : T55 BNTJ B1 C1 HQ &IH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,3-Dimethyl-2-azabicyclo(3.3.0)-octanol-(8) hydrojodid
   * GR 888
   * Octahydro-1,2-dimethylcyclopenta(b)pyrrol-6-ol hydriodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5075 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HPPAAL Helvetica Physiologia et Pharmacologica Acta.  (Basel, Switzerland)
   V.1-26, 1943-68. Discontinued.  Volume(issue)/page/year: 16,277,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 960 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HPPAAL Helvetica Physiologia et Pharmacologica Acta.  (Basel, Switzerland)
   V.1-26, 1943-68. Discontinued.  Volume(issue)/page/year: 16,277,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HPPAAL Helvetica Physiologia et Pharmacologica Acta.  (Basel, Switzerland)
   V.1-26, 1943-68. Discontinued.  Volume(issue)/page/year: 16,277,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HPPAAL Helvetica Physiologia et Pharmacologica Acta.  (Basel, Switzerland)
   V.1-26, 1943-68. Discontinued.  Volume(issue)/page/year: 16,277,1958
 
                            *** END OF RECORD ***