*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GZ0591900
CHEMICAL NAME           : 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one,
                          1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-
                          decahydro-3-formyl-4a-beta,7b-beta,9-beta,9a-alpha-te
                          trahydroxy-1,1,6,8-al pha-tetramethyl-, 9a-acetate,
                          9-myristate
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C36-H54-O7
MOLECULAR WEIGHT        : 598.90
WISWESSER LINE NOTATION : L E3 B675 MV IU NUTJ BQ C1 DOV13 EOV1 F1 F1 JVH LQ N1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * PAMA
   * Phorbol-9-myristate-9a-acetate-3-aldehyde
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg/27W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,2644,1979
 
                            *** END OF RECORD ***