*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GZ0660000
CHEMICAL NAME           : 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one,
                          1,1a-beta,1b-alpha,4,4a,7a-beta,7b,8,9,9a-
                          decahydro-4a-alpha,7b-beta,9-alpha,9a-beta-tetrahydro
                          xy-3-(hydroxymethyl)- 1,1,6,8-beta- tetramethyl-,
                          9a-laurate (S)-(+) 9-(2-methylbutyrate)
CAS REGISTRY NUMBER     : 63040-44-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C37-H58-O8
MOLECULAR WEIGHT        : 630.95
WISWESSER LINE NOTATION : L E3 B675 MV IU NUTJ BQ C1 DOVY2&1 EOV11 F1 F1 JO1 LQ
                          N1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Phorbol laurate, (+)-S-2-methylbutyrate
   * Phorbol monolaurate mono(S)-(+)-2-methylbutyrate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 24 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   NATWAY Naturwissenschaften.  (Springer-Verlag, Heidelberger Platz 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1913-  Volume(issue)/page/year:
   54,282,1967
 
                            *** END OF RECORD ***