*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GZ0670000
CHEMICAL NAME           : 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one,
                          1,1a-beta,1b-alpha,2,3,4,4a,7a-beta,7b,8,9,9a-
                          dodecahydro-4a-alpha,7b-beta,9-alpha,9a-beta-tetrahyd
                          roxy-3-(hydroxymethyl )-1,1,6,8-beta- tetramethyl-,
                          9a-acetate 9-myristate
CAS REGISTRY NUMBER     : 66731-42-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C36-H58-O8
MOLECULAR WEIGHT        : 618.94
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 2,3-Dihydrophorbol myristate acetate
   * DPMA
   * Phorbol, 2,3-dihydro-, acetate myristate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37 mg/kg/31W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,921,1978
 
                            *** END OF RECORD ***